Sobering statistics:

  • Arteriosclerosis is the most common form of heart disease.
  • It begins early in life: 1 out of 6 teenagers (ages 12 to 19) have significant degree of coronary disease (Cleveland Clinic Foundation, reported in 1999). The Bogalusa Heart Study (University of Tulane) reports signs of arteriosclerosis in children as young as 3 years old.
  • At age 45,  75% of individuals have significant degree of arteriosclerosis. Over 80% of people over 65 years of age are affected.
  • It is responsible for more than 50% of the total mortality in the nation yearly, it causes more than 1.2 million heart attacks of which over 500,000 die. It causes also, more than 750,000 strokes per year.
  • The causes of arteriosclerosis are well known in over 90% of cases and occur usually through a constellation of "risk factors".

How the heart works:

View this video to see how the lack of blood supply affects the heart, the brain, the kidneys and lower extremities. You can see how the progressive obstruction in the arteries of the heart, brain, kidneys and lower extremities lead to events.

 

Normal Heart

 

The heart is a hollow muscle that weighs 300 grams. It beats regularly at 60 to 90 beats per minute as it empties into the aorta 60 cubic centimeters (2 ounces) of blood per beat. This is 5 liters of blood per minute, 300 liters per hour or 7200 liters of blood per day. Blood is distributed throughout the body at this rate if the arteries are healthy and unrestricted.

The heart pumps blood rich in oxygen and nutrients to all parts of the body using it's own electrical system. it allows the heart to contract regularly in a sequential manner. The rate of output can be regulated by other factors such as emotional and physical stress, by increasing flow 3 to 4 times the normal rate. When there is arteriosclerosis, the blood supply to the heart muscle is limited.

The normal heart is a strong, hardworking pump made of muscle tissue. It's about the size of a person's fist.
The heart has four chambers. The upper two chambers are the right atrium and left atrium, and the lower two are the right ventricle and left ventricle (see Figure A in diagram). Blood is pumped through the chambers, aided by four heart valves. The valves open and close to let the blood flow in only one direction. The closing of the valves originate the heart sounds.

The four heart valves are:
1) tricuspid valve, located between the right atrium and the right ventricle
2) pulmonary valve, between the right ventricle and the pulmonary artery
3) mitral valve, between the left atrium and left ventricle
4) aortic valve, between the left ventricle and the aorta

Each valve has a set of "flaps" (also called leaflets or cusps). The mitral valve normally has two flaps; the others have three flaps.

Dark bluish blood, low in oxygen, flows back to the heart after circulating through the body. It returns to the heart through veins and enters the right atrium. This chamber empties blood through the tricuspid valve (B) into the right ventricle. The right ventricle pumps the blood under low pressure through the pulmonary valve into the pulmonary artery. From there the blood goes to the lungs where it gets fresh oxygen (C). After the blood is refreshed with oxygen, it's bright red. Then it returns by the pulmonary veins to the left atrium. From there it passes through the mitral valve (D) and enters the left ventricle. The left ventricle pumps the red oxygen-rich blood out through the aortic valve into the aorta (E). The aorta takes blood to the body's general circulation. The blood pressure in the left ventricle is the same as the pressure measured in the arm.

What causes a heart attack?

A heart attack occurs when there is restriction to blood flow due to abnormalities in the lining of the arteries that supply blood to the heart. If there is partial restriction in the arteries angina is experienced. If restriction is total and sudden, a heart attack occurs. Most heart attacks are produced by a sudden rupture of a plaque in the lining of a coronary artery. A clot forms around the plaque which blocks the artery. The blockage causes an area of the heart to be deprived of circulation making that area of the heart to die.

Warning signs of a heart attack:

Each year more than 1 million Americans die of cardiovascular diseases, more than from all other diseases, homicides, suicides, and auto accidents combined. Each year approximately 1.2 million heart attacks occur. Nearly 45% of first heart attacks prove fatal. Most deaths occur during the first hour. 675,000 attacks take place in people under the age of 65.

Below are warning signs: 
     - Pressure, fullness, tightness or pain in the chest, lasting 5 minutes or longer.
     - Constant indigestion-like discomfort.
     - Chest pain that moves to the shoulders, arms, neck, jaw or back.
     - Lightheadedness, dizziness, fainting, sweating, or sick stomach
     - Unexplained shortness of breath
     - Unexplained anxiety, weakness, or tiredness
     - Palpitations, a cold sweat, or paleness

What causes a stroke in the brain?

85% of strokes occur due to a similar process to a heart attack; a clot is formed when a plaque ruptures in an artery in the brain. This causes an area of the brain to be destroyed due to lack of circulation. This type of stroke is a thrombotic stroke. 15% of strokes are hemorrhagic and are caused by a rupture in an artery in the brain. This is usually due to severe, untreated hypertension or to abnormalities of the arteries either acquired or congenital.

Warning signs of a stroke:

     - Sudden numbness or weakness of the face, arm or leg, especially on one side of the body.
     - Sudden confusion, trouble speaking or understanding.
     - Sudden trouble seeing in one or both eyes.
     - Sudden trouble walking, dizziness, loss of balance or coordination.
     - Sudden, severe headache with no known cause

Note: If you or someone with you has one or more of these signs, don't delay! Immediately call 9-1-1 or the emergency medical services ( EMS ) number, an ambulance (ideally with advanced life support) can be sent for you. Also, check the time so you'll know when the first symptoms appeared. It's very important to take immediate action. If given within three hours of the start of symptoms, a clot-busting drug can reduce long-term disability for the most common type of stroke.

Many people have a distinctive sound in the neck called "carotid bruit" usually detected by your doctor when he or she listens for it with a stethoscope along your neck, in both sides. If this abnormal sound is present, it indicates a blockage in the area. This blockage is amenable to correction by surgery before a stroke develops

What is cardiac arrest?

Cardiac arrest is the final event that leads to death. Following a heart attack, cardiac arrest can occur as a consequence of severe arrhythmias. The worst type of arrhythmia is ventricular fibrillation, which is seen in 90% of cardiac arrests. Ventricular fibrillation is like an electrical storm of irregular heart beats causing ineffectual contractions in the heart. Without effective contractions, blood is not pumped and circulation stops resulting in death; 10% of cardiac arrests result from ventricular asystole or lack of heartbeats that prevent circulation and result in death. If there is timely intervention before irreparable damage to the brain occurs (3 minutes) proper help could save a life.

  What is Sudden Death?

 Sudden Death is an unexpected event. While the most common cause is a heart attack (75%) , it may occur due to other causes. The following conditions predispose to sudden cardiac death:

  • A  congenital prolongation of the Q-T interval in the electrocardiogram,  such as the Jervell-Lange-Nielsen Syndrome. Other conditions of prolonged  Q-T interval may be acquired,  by the use of certain pro-arrhythmic drugs, such as quinidine, procainamide, sotalol, amiodorone , certain antibiotics, tranquilizers or anti-depressants.  When the Q-T interval is prolonged, the heart is vulnerable for the development  of severe arrhythmias.

  •  Some recreational drugs like cocaine, amphetamines may induce sudden death by enhancing the onset of fatal arrhythmias.

  • The Brugada syndrome, a congenital condition that shows right bundle branch block in the electrocardiogram, may be the cause of fatal arrhythmias.

  • The ARVD syndrome (right ventricle dysplasia), where the muscle of the right ventricle is replaced by lipoid tissue. This condition has been known to be the cause of sudden death in young people.

  • The Wolff-Parkinson-Syndrome, congenital condition, where there is a short cut in the electrical transmission between the right atrium and the ventricles. WPW may cause also sudden death due to fatal arrhythmias.

  • The IHSS syndrome (familial idiopathic sub-valvular aortic stenosis). This condition is responsible for many cases of sudden death in young athletes. IHSS has an incidence of 1: 500 people

  •  Aortic stenosis , acquired or congenital.

  • Hypertrophy of the left ventricle (most commonly due to long standing arterial hypertension) is not an infrequent underlying condition in some cases of sudden death.

.Signs of cardiac arrest:

Signs of cardiac arrest strike suddenly and many times without warning. Here are the signs:
     - Sudden loss of responsiveness.
     - No response to gentle shaking.
     - No normal breathing. The victim does not take a normal breath when you check for several seconds.
     - No signs of circulation.
     - No movement or coughing. 

What can you do for the victim?

  • If cardiac arrest occurs, call 911 and begin CPR immediately. If an automated external defibrillator (AED) is available and someone is trained to use it is nearby, involve them.
  • Cardiopulmonary resuscitation (CPR) is an emergency procedure used to treat victims of cardiac and respiratory arrest.
  • CPR can be done in a hospital with drugs and special equipment or as a first-aid technique. In either case it is done with great urgency to avoid the brain damage or death that result from three to six minutes without oxygen.
  • The first-aid procedure combines external heart massage (to keep the blood flowing through the body) with artificial respiration (to keep air flowing in and out of the lungs). The victim is placed face up and prepared for artificial respiration.
  • The person administering CPR places his or her hands (one on top of the other, with fingers interlocked) heel down on the victim's breastbone, leans forward, and makes 30 quick, rhythmical compressions (at a rate of about one per second) of about 2 in. (5 cm). The recommended ratio is 30 compressions to 2 ventilations (New Guidelines 2006). The two breaths are administered using the mouth-to-mouth method of artificial respiration. CPR for infants and children differs in the ratio of compressions to breaths, and the compression of the chest is only 1 to 1.5 in. (2.5 to 3.8 cm). Ideally two people do the procedure, one to give mouth-to-mouth artificial respiration and one to apply external heart massage, and special training is recommended. 
  •  Note:  It has been established that the most important component in cardiopulmonary resuscitacion is the cardiac massage. It has been proven that cardiac massage without artificial ventilation results in half as many neurological complications among the survivors. The final guidelines for CPR are being reviewed.                                                                                                                                                

Surviving a heart attack when alone. Coughing can save your life!

If you experience severe pain in the chest that starts to radiate down your arm or into your jaw, feel like fainting and you are alone: 
     - Remember, without help, the person whose heart stops beating properly and who begins to feel faint, has only 30 seconds        before losing consciousness.
     - Start coughing very vigorously, at least every 3 seconds.  Take a deep breathe before each cough.
     - The cough should be deep and prolonged, as when producing sputum from deep inside the chest.
     - Repeat the cough without letup until help arrives.

Deep breaths get oxygen into the lungs and coughing movements squeeze the heart to keep the blood circulating maintaining a blood pressure. Doing this procedure prolongs the "window" of survival allowing time for help to arrive. They are reported cases of prolongation of this "window" from the critical 3 minutes to 30  minutes resulting in a successful resuscitation. We call this procedure “CPR Thyself”. Remember, this procedure should not be employed after any episode of chest pain; Only if loss of consciousness is about to happen.

Cardiovascular disease risk factors (heart attack and stroke):

Risk factors induce arteriosclerosis with cardiac and cerebrovascular disease being the main manifestation. Arteriosclerosis is the same thing as “hardening of the arteries”. We need to neutralize risk factors. Some risk factors can be controlled through changes in life style while other risk factors need to be monitored with medical testing, medication, and management. 
     - SMOKING
     - DIABETES, PRE-DIABETES or Syndrome X
     - HYPERLIPIDEMIA (high cholesterol and other lipids)
     - ARTERIAL HYPERTENSION (high blood pressure)
     - SEDENTARY LIFESTYLE (physical inactivity)
     - POOR DIET
     - OVERWEIGHT, OBESITY
     - INFLAMMATION
     - ELEVATED LEVELS OF HOMOCYSTEINE
     - EMOTIONAL FACTORS (depression, anxiety, and hostility)
     - HEREDITY (genetic factors)

      -OTHER NUTRITIONAL AND ENVIRONMENTAL FACTORS

-Heart healthy life style principles:

The following are the 5 principles you should follow to prevent heart attacks and strokes, diseases that can cause early death, illness, or serious debilitation. The 5principles are based on research and findings that are current and have been shown to clearly prevent cardiovascular disease. We recommend that one follow and incorporate all the principles to live a healthy lifestyle.
   
1) Research your risk factors:
Go through the list of risk factors and rate yourself to establish areas of risk. For example: Is there heart disease in your family? Is your HDL too low? Do you have diabetes? As you go through the course, keep all the risk factors in mind and focus on the areas in which you need improvement. At the end of each session, record your long-term goal and your short-term goal for the risk area discussed. For some risk factors, you may need to get a blood test and speak with a physician. For other risk areas, you may be able to establish whether or not you are at risk by using the information provided in this course. At the end of the 11-session course you should have your assessment of risk areas that need attention and your list of both long term and short-term goals for each risk factor that applies to you. See lesson two to learn about the risks of high lipids.

View this table to rate your risk factors.

The table indicates the likelihood of developing manifestations of heart disease (angina or heart attack).

Any man with at least 12 points or woman with 19 points has a 10% risk of developing heart disease manifestations within 10 years and therefore should be treated with lipid lowering agents, regardless of age and individual blood pressure, total cholesterol or HDL-C. There is evidence that elevated levels of C-Reactive Protein alone (over 2.5) have a very high predictive risk importance, even more than LDL values. This is an indication for treatment using statins or other lipid lowering drugs as well as aspirin to reduce inflammation.

2) Practice heart healthy eating:
Research has shown that diet does affect cardiovascular health. Specifically, a poor diet, rich in fats and simple carbohydrates can build plaques in the arteries and create blockages, which eventually will result in a heart attack or affect the brain with a stroke. Following a heart healthy diet that is low in saturated fat, high in fiber and vegetables, containing many nutrients (anti-oxidants, vitamins) can prevent the arteriosclerotic process. More information will follow on the new food pyramid, healthy eating, optimal weight and girth. Recent medical research proves that cardiovascular disease can be reversed through diet.

3) Maintain physical fitness:
Research has shown that regular, moderate exercise can positively influence your LDL, HDL, your mood, your weight, and diabetes. We recommend a variety of exercise options with tables to determine the most effective exercise program for you. See lesson four to learn more the about the risks of inactivity, high blood pressure and what you can do.

4) Maintain emotional fitness:
Studies indicate a correlation between depression, hostility, stress and heart disease. Stress produces hormones that can contribute to plaque build up in the arteries. We offer you techniques to manage your stress as well as the latest cognitive approaches for dealing with hostility and depression. See Session Five to learn new techniques to deal with stress effectively.

5) Foster friendship and connection:
Dr. Dean Ornish did the pioneer research that showed the correlation between a healthy heart and a loving heart. He found people who were connected with family or friends had less heart disease than those who are socially isolated. A commitment to foster social connection through work, volunteerism, spirituality, and family can boost the immune system and reduce the stresses of living in today’s complicated world.

Following these 5 Principles of heart healthy living can help prevent or even reverse heart disease.  Many of us may have to enter a state of TLC – total life style change.

Note: Many people put off getting the care that could save lives because they often do not take the warning signs seriously. Although chest pain is usually the most common sign, some people have heart attacks without having chest pain. That is why is important to be aware of other warning signs as well, such as unexplained dizziness, epigastric discomfort, left shoulder or jaw pain, shortness of breath without apparent reason.  Anyone who has any of these signs for five minutes or longer should have medical attention right away. Call an ambulance (dial 9-1-1) or have someone drive you to the nearest emergency room, you could be having a heart attack. Do not drive yourself, it could be dangerous to you or others.

Many people think a heart attack is sudden and intense, like in the "movies", where a person clutches his or her chest and falls over. The truth is that many heart attacks start slowly, as a mild pain or discomfort. If you feel such a symptom, you may not be sure what's wrong. Your symptoms may even come and go. Even those who have had a heart attack may not recognize the symptoms of the next attack. Women may think they're not at risk of having a heart attack, but they are and commonly they  have atypical symptoms.

Learn the signs – but also remember if you're not sure it's a heart attack, you should still have it checked out. Fast action can save lives – maybe your own.

Act in time to heart attack signs:

The dramatic, moving stories of three heart attack survivors and their families illustrate the importance of heeding heart attack warning signs and seeking medical care quickly. They vividly convey how a real heart attack may differ from the stereotypical "movie heart attack" and how getting immediate treatment can save lives. The warm and sympathetic narration by an emergency department physician explains what a heart attack is, the treatments that can save lives if given quickly, why many heart attack victims delay seeking care, and how to make a heart attack survival plan. Useful for health fairs, medical waiting rooms, community groups, and home viewing. Video Play Time: 13 minutes.

Act in Time To Heart Attack Signs – Video

You must also have RealPlayer version 5.0 or higher on your computer and configured to work with the WWW browser (Netscape, Internet Explorer, etc). If you do not have RealPlayer, you may download a free copy from Real Networks. The latest version is RealPlayer 8. [Information about RealPlayer]

Common questions:

Q: Are there geographical differences with mortality due to cardiovascular disease among the states in the USA?  
A: Yes.

View chart.

States colored in red:  Mississippi, Kentucky, Tennessee, West Virginia, Oklahoma, Louisiana, Alabama and Indiana, have the worst statistics (possibly due to diet ? -rich in animal fats, too much fried food ?)

Q: How does age affect risk factors? 
A: Aging itself should not be considered a risk factor; however, the older a person gets the longer he/she is exposed to the risk factors for the development of cardiovascular disease.

Q: Does occupation and level of education effect risk levels?
A: Yes. Certain occupations that involve high stress on a continual basis make people more prone to allow the risk factors to occur. People in jobs that are sedentary often are at greater risk. Lack of education can put people at higher risk as well.This web site brings you important information on heart disease to help you strive for wellness.

Q: Do married people stay healthier? 
A: Yes, because they are less isolated, more connected, and sometimes less stressed due to the emotional support factor. It can also be said “two heads are better than one”;  therefore, a couple may have more health information at hand.

Q: Do socioeconomic factors influence cardiovascular heart disease? 
A: Absolutely. People with adequate financial means get help more easily, have access to more information, and have more time or freedom to attend to health issues. In certain professions there is little opportunity for education and information. Information is vital to help people prevent illness. This web site brings you the latest research and information so that you can be a member of your own wellness team.

Q: In what countries do people have less cardiovascular disease than the USA?

View rankings.

A: Japan has the least heart disease because they are leaner in general, eat more fish and vegetables and have a higher degree of activity than in many other countries. France, Spain and Italy are the next in line in terms of the lowest incidence of heart disease. It is believed that the social dining conditions of long and pleasurable meals with lots of conversation and connection, one or two glasses of red wine, the Mediterranean diet, as well as a high degree of physical activity helps to keep these groups more heart healthy.

Q: Are children at risk for cardiovascular disease? 
A: Yes. The lipid profile should be checked in everyone before the age of 20 especially if there is a family history of heart disease or high cholesterol.

Q: Are women and men different regarding cardiovascular disease?
A: Yes. There are substantial differences between men and women in reference to cardiovascular disease. Some facts are emerging according to the latest medical research.

For reasons that are unclear, women have been left out of major research studies in cardiovascular disease until very recently.  Most statistics regarding heart attacks and strokes have been gathered primarily by studying the male population. In all fairness this is unjustified since women compose a little over half of the population.

Time of onset: Cardiovascular disease usually shows itself 15 years later in women than in men.
Some of the reasons are:
     - There is a protective effect of female hormones prior to menopause (still debatable).
     - Women smoke less than men (at least until the last few years).
     - There are more Type “A” personalities among men than women.

During the previous century women have been out of the main work force, therefore they have been somewhat protected from wear and tear that comes with exposure to stress, hostile environment, competition, and challenge which cause men to become aggressive risk takers. However, in modern times women are narrowing the “gap” very rapidly by entering the man’s world. :Women in general are gentler, softer, and more patient. They do not discharge adrenaline as often and as intensively as men do. Women have, as rule higher levels of HDL- cholesterol. Researchers do not know why. HDL is known to have a significant protective effect against arteriosclerosis.

Diagnosis and treatment: Cardiovascular disease is the leading cause of death among women in this country, surpassing cancer of the breast and all the other forms of cancer. However while the incidence of cardiovascular disease mortality in men has been decreasing since 1970, it is increasing for women. About 500,000 women per year suffer heart attacks. Of these, 42% die within a year. Men suffer about 670,000 heart attacks per year, but only 24% of them die during the first year. The higher mortality among women after a heart attack has to do with differences in presenting symptoms, response to treatment, and other factors that relate to older age at onset of cardiovascular disease.

Symptoms: Symptoms can be misleading in women. More women than men have chest pain that is Indistinguishable from angina pectoris, even though they have normal coronary arteries. (proven by coronary arteriography). Clinicians underestimate findings and adverse prognostic significance of stress-test abnormalities found in women. For this reason fewer women are referred for cardiac catheterization and revascularization procedures after abnormal stress tests. The presence of risk factors associated with cardiovascular disease and their control apply equally to men and women.

Therapeutic procedures for revascularization (angioplasty, stent placement and coronary bypass) have a higher rate of complications as well as higher mortality in women. One reason why women do less well after coronary bypass may be due to the fact that the internal mammary artery (as opposed to vein grafts) is less frequently used in them. It is unclear why.

Cardiac rehabilitation benefits at least 13% of men after a heart attack but only 7% of women. Physicians refer fewer women for cardiac rehabilitation. This could also explain why women do less well than men following a heart attack.

Hormonal Replacement Therapy (HRT): The latest information regarding risks versus benefits on the use of HRT in women (typically 0.625-mg estrogens plus 2.5 mg progesterone daily) is as follows:

     Risks:
     - More heart attacks and strokes occur in post-menopausal women during the first year of therapy.
     - More breast cancer and more incidents with blood clots (leg veins and lungs).

     Benefits:
     - Less cancer of the rectum and colon.
     - Less osteoporosis (therefore less spine and hip fractures).
     - There are some reports that HRT may delay the onset of Alzheimer disease.
     - Less incidence of cancer of the endometrium.
     - Fewer hot flashes.

The proper choice regarding the use of HRT remains a difficult one to make. Pros and cons have to be carefully weighed. In our opinion women should make the final decision after all the available evidence is presented to them. Sometimes hot flashes are so unbearable that some women are willing to take a chance using hormone replacement therapy.

There is however a group of medications used for depression that effectively suppress hot flashes: Paxil, Celexa, Prozac and Neurontonin, and anti-epileptic drug. Evista, used for osteoporosis and treatment of Cancer de the breast  is also effective for suppressing hot flashes. More active research in the subject is being done.

Q: Are we improving?
A: Yes, we are indeed. The average life span in 1900 was only 47 years for men and women. In the year 2000 the life average has been extended to 74.5 years for men and 79 years for women. The latest numbers for 2005 show an increase to 77.2 years for both sexes. This is an increase of 30 years in longevity in one century! This is due to the great medical advances that have taken place. Following heart attacks and strokes mortality has declined do to early diagnosis of the "event ", prompt treatment with "clot busters", angioplasty, stent implants as well as other revascularization procedures. These procedures give individuals a second, third or even higher chance to live. However, the incidence of arteriosclerosis is not declining because preventive measures are not being widely used despite our present knowledge.

Updated July 18th, 2007

© Cardio Wellness, Inc. 2004 cardiowellness@comcast.net