Sobering
statistics:
- Arteriosclerosis is the most common form of heart disease.
- It begins early in life: 1 out of 6 teenagers (ages 12 to 19)
have significant degree of coronary disease (Cleveland Clinic
Foundation, reported in 1999). The Bogalusa Heart Study (University
of Tulane) reports signs of arteriosclerosis in children as young
as 3 years old.
- At age 45, 75% of individuals have significant degree
of arteriosclerosis. Over 80% of
people over 65 years of age are affected.
- It is responsible for more than 50% of the total mortality in
the nation yearly, it causes more than 1.2 million heart attacks
of which over 500,000 die. It causes also, more than 750,000
strokes per year.
- The causes of arteriosclerosis are well known in over 90% of
cases and occur usually through a constellation of "risk
factors".
How
the heart works:
View
this video to see how the lack of blood supply affects the
heart, the brain, the kidneys and lower extremities. You can see
how the progressive obstruction in the arteries of the heart, brain,
kidneys and lower extremities lead to events.
Normal Heart
The heart is a hollow muscle that weighs 300 grams. It beats regularly
at 60 to 90 beats per minute as it empties into the aorta 60 cubic
centimeters (2 ounces) of blood per beat. This is 5 liters of blood
per minute, 300 liters per hour or 7200 liters of blood per day.
Blood is distributed throughout the body at this rate if the arteries
are healthy and unrestricted.
The heart pumps blood rich in oxygen and
nutrients to all parts of the body using it's own electrical system.
it allows the heart to contract regularly in a sequential manner.
The rate of output can be regulated by other factors such as emotional
and physical stress, by increasing flow 3 to 4 times the normal
rate. When there is arteriosclerosis, the blood supply to the heart
muscle is limited.
The normal heart is a strong, hardworking
pump made of muscle tissue. It's about the size of a person's fist.
The heart has four chambers. The upper two chambers are the right
atrium and left atrium, and the lower two are the right ventricle
and left ventricle (see Figure A in diagram). Blood is pumped through
the chambers, aided by four heart valves. The valves open and close
to let the blood flow in only one direction. The closing of the
valves originate the heart sounds.
The four heart valves are:
1) tricuspid valve, located between the right atrium and the right
ventricle
2) pulmonary valve, between the right ventricle and the pulmonary
artery
3) mitral valve, between the left atrium and left ventricle
4) aortic valve, between the left ventricle and the aorta
Each valve has a set of "flaps"
(also called leaflets or cusps). The mitral valve normally has two
flaps; the others have three flaps.
Dark bluish blood, low in oxygen, flows back
to the heart after circulating through the body. It returns to the
heart through veins and enters the right atrium. This chamber empties
blood through the tricuspid valve (B) into the right ventricle.
The right ventricle pumps the blood under low pressure through the
pulmonary valve into the pulmonary artery. From there the blood
goes to the lungs where it gets fresh oxygen (C). After the blood
is refreshed with oxygen, it's bright red. Then it returns by the
pulmonary veins to the left atrium. From there it passes through
the mitral valve (D) and enters the left ventricle. The left ventricle
pumps the red oxygen-rich blood out through the aortic valve into
the aorta (E). The aorta takes blood to the body's general circulation.
The blood pressure in the left ventricle is the same as the pressure
measured in the arm.
What
causes a heart attack?
A heart attack occurs when there is restriction
to blood flow due to abnormalities in the lining of the arteries
that supply blood to the heart. If there is partial restriction
in the arteries angina is experienced. If restriction is total and
sudden, a heart attack occurs. Most heart attacks are produced by
a sudden rupture of a plaque in the lining of a coronary artery.
A clot forms around the plaque which blocks the artery. The blockage
causes an area of the heart to be deprived of circulation making
that area of the heart to die.
Warning
signs of a heart attack:
Each year more than 1 million Americans die
of cardiovascular diseases, more than from all other diseases, homicides,
suicides, and auto accidents combined. Each year approximately 1.2
million heart attacks occur. Nearly 45% of first heart attacks prove
fatal. Most deaths occur during the first hour. 675,000 attacks
take place in people under the age of 65.
Below are warning signs:
- Pressure, fullness, tightness or
pain in the chest, lasting 5 minutes or longer.
- Constant indigestion-like discomfort.
- Chest pain that moves to the shoulders,
arms, neck, jaw or back.
- Lightheadedness, dizziness, fainting,
sweating, or sick stomach
- Unexplained shortness of breath
- Unexplained anxiety, weakness, or
tiredness
- Palpitations, a cold sweat, or paleness
What
causes a stroke in the brain?
85% of strokes occur due to a similar process
to a heart attack; a clot is formed when a plaque ruptures in an
artery in the brain. This causes an area of the brain to be destroyed
due to lack of circulation. This type of stroke is a thrombotic
stroke. 15% of strokes are hemorrhagic and are caused by a rupture
in an artery in the brain. This is usually due to severe, untreated
hypertension or to abnormalities of the arteries either acquired
or congenital.
Warning
signs of a stroke:
- Sudden
numbness or weakness of the face, arm or leg, especially on one
side of the body.
- Sudden confusion, trouble speaking
or understanding.
- Sudden trouble seeing in one or
both eyes.
- Sudden trouble walking, dizziness,
loss of balance or coordination.
- Sudden, severe headache with
no known cause
Note:
If you or someone with you has one or more of these signs,
don't delay! Immediately call 9-1-1 or the emergency medical
services ( EMS ) number, an ambulance (ideally with advanced life support)
can be sent for you. Also, check the time so you'll know when the
first symptoms appeared. It's very important to take immediate action.
If given within three hours of the start of symptoms, a clot-busting
drug can reduce long-term disability for the most common type of
stroke.
Many people
have a distinctive sound in the neck called "carotid bruit"
usually detected by your doctor when he or she listens for it with
a stethoscope along your neck, in both sides. If this abnormal
sound is present, it indicates a blockage in the area. This blockage
is amenable to correction by surgery before a stroke develops
What
is cardiac arrest?
Cardiac arrest is the final event that leads
to death. Following a heart attack, cardiac arrest can occur as
a consequence of severe arrhythmias. The worst type of arrhythmia
is ventricular fibrillation, which is seen in 90% of cardiac arrests.
Ventricular fibrillation is like an electrical storm of irregular
heart beats causing ineffectual contractions in the heart.
Without effective contractions, blood is not pumped and circulation
stops resulting in death; 10% of cardiac arrests result from ventricular asystole or lack of heartbeats that prevent circulation and result
in death. If there is timely intervention before irreparable damage
to the brain occurs (3 minutes) proper help could save a life.
What is Sudden Death?
Sudden
Death is an unexpected event. While the most common cause is a heart
attack (75%) , it may occur due to other causes. The following
conditions predispose to sudden cardiac death:
-
A congenital prolongation of the Q-T interval in the
electrocardiogram, such as the Jervell-Lange-Nielsen
Syndrome. Other conditions of prolonged Q-T interval may
be acquired, by the use of certain
pro-arrhythmic drugs, such as quinidine, procainamide,
sotalol, amiodorone , certain antibiotics, tranquilizers or
anti-depressants. When the Q-T interval is prolonged, the
heart is vulnerable for the development of severe
arrhythmias.
-
Some recreational drugs like
cocaine,
amphetamines may induce sudden death by enhancing the onset of
fatal arrhythmias.
-
The Brugada syndrome, a congenital
condition that shows right bundle branch block in the
electrocardiogram, may be the cause of fatal arrhythmias.
-
The ARVD syndrome (right ventricle
dysplasia), where the muscle of the right ventricle is replaced
by lipoid tissue. This condition has been known to be the cause
of sudden death in young people.
-
The Wolff-Parkinson-Syndrome,
congenital condition, where
there is a short cut in the electrical transmission between the
right atrium and the ventricles. WPW may cause also sudden death
due to fatal arrhythmias.
-
The IHSS syndrome (familial idiopathic sub-valvular
aortic stenosis). This condition is responsible for many cases
of sudden death in young athletes. IHSS has an incidence of 1: 500
people
-
Aortic stenosis , acquired or
congenital.
-
Hypertrophy of the left ventricle (most
commonly due to long standing arterial hypertension) is not an
infrequent underlying condition in some cases of sudden death.
.Signs
of cardiac arrest:
Signs of cardiac arrest strike suddenly
and many times without warning. Here are the signs:
- Sudden loss of responsiveness.
- No response to gentle shaking.
- No normal breathing. The victim
does not take a normal breath when you check for several seconds.
- No signs of circulation.
- No movement or coughing.
What
can you do for the victim?
- If cardiac arrest occurs, call 911 and begin CPR immediately.
If an automated external defibrillator (AED) is available and
someone is trained to use it is nearby, involve them.
- Cardiopulmonary resuscitation (CPR) is an emergency procedure
used to treat victims of cardiac and respiratory arrest.
- CPR can be done in a hospital with drugs and special equipment
or as a first-aid technique. In either case it is done with great
urgency to avoid the brain damage or death that result from three
to six minutes without oxygen.
- The first-aid procedure combines external heart massage (to
keep the blood flowing through the body) with artificial respiration
(to keep air flowing in and out of the lungs). The victim is placed
face up and prepared for artificial respiration.
- The person administering CPR places his or her hands (one on
top of the other, with fingers interlocked) heel down on the victim's
breastbone, leans forward, and makes 30 quick, rhythmical compressions
(at a rate of about one per second) of about 2 in. (5 cm).
The recommended ratio is 30 compressions to 2 ventilations (New Guidelines
2006). The two breaths are administered using the
mouth-to-mouth method of artificial respiration. CPR for infants and children differs
in the ratio of compressions to breaths, and the compression of
the chest is only 1 to 1.5 in. (2.5 to 3.8 cm). Ideally two people
do the procedure, one to give mouth-to-mouth artificial respiration
and one to apply external heart massage, and special training
is recommended.
- Note: It has been established that the
most important component in cardiopulmonary resuscitacion is the
cardiac massage. It has been proven that cardiac massage without
artificial ventilation results in half as many neurological
complications among the survivors. The final guidelines for CPR
are being reviewed.
Surviving
a heart attack when alone. Coughing can save your life!
If you experience severe pain in the chest
that starts to radiate down your arm or into your jaw, feel
like fainting and you
are alone:
- Remember, without help, the person
whose heart stops beating properly and who begins to feel faint,
has only 30 seconds before
losing consciousness.
- Start coughing very vigorously,
at least every 3 seconds. Take a deep breathe before
each cough.
- The cough should be deep and
prolonged, as when producing sputum from deep inside the chest.
- Repeat the cough without letup until help
arrives.
Deep breaths get oxygen into the lungs and
coughing movements squeeze the heart to keep the blood circulating
maintaining a blood pressure. Doing this procedure prolongs the
"window" of survival allowing time for help to arrive. They are
reported cases of prolongation of this "window" from the critical 3
minutes to 30 minutes resulting
in a successful resuscitation. We call this procedure “CPR
Thyself”. Remember, this procedure should not be employed
after any episode of chest pain; Only if loss of consciousness is
about to happen.
Cardiovascular
disease risk factors (heart attack and stroke):
Risk factors induce arteriosclerosis with
cardiac and cerebrovascular disease being the main manifestation.
Arteriosclerosis is the same thing as “hardening of the arteries”.
We need to neutralize risk factors. Some risk factors can be controlled
through changes in life style while other risk factors need to be
monitored with medical testing, medication, and management.
- SMOKING
- DIABETES, PRE-DIABETES
or Syndrome X
- HYPERLIPIDEMIA
(high cholesterol and other lipids)
- ARTERIAL HYPERTENSION
(high blood pressure)
- SEDENTARY LIFESTYLE
(physical inactivity)
- POOR DIET
- OVERWEIGHT, OBESITY
- INFLAMMATION
- ELEVATED LEVELS
OF HOMOCYSTEINE
- EMOTIONAL FACTORS
(depression, anxiety, and hostility)
- HEREDITY (genetic
factors)
-OTHER
NUTRITIONAL AND ENVIRONMENTAL FACTORS
-Heart
healthy life style principles:
The following are the 5 principles you should
follow to prevent heart attacks and strokes, diseases that can cause
early death, illness, or serious debilitation. The 5principles are
based on research and findings that are current and have been shown
to clearly prevent cardiovascular disease. We recommend that one
follow and incorporate all the principles to live a healthy
lifestyle.
1) Research your risk factors:
Go through the list of risk factors and rate yourself to
establish areas of risk. For example: Is there heart disease in
your family? Is your HDL too low? Do you have diabetes? As you go
through the course, keep all the risk factors in mind and focus
on the areas in which you need improvement. At the end of each session,
record your long-term goal and your short-term goal for the risk
area discussed. For some risk factors, you may need to get a blood
test and speak with a physician. For other risk areas, you may be
able to establish whether or not you are at risk by using the information
provided in this course. At the end of the 11-session course you
should have your assessment of risk areas that need attention and
your list of both long term and short-term goals for each risk factor
that applies to you. See lesson two to learn about the risks of
high lipids.
View
this table to rate your risk factors.
The table indicates the likelihood of developing
manifestations of heart disease (angina or heart attack).
Any man with at least 12 points or woman
with 19 points has a 10% risk of developing heart disease manifestations
within 10 years and therefore should be treated with lipid
lowering agents, regardless of age and individual blood pressure,
total cholesterol or HDL-C. There is evidence that elevated levels
of C-Reactive Protein alone (over 2.5) have a very high predictive
risk importance, even more than LDL values. This is an indication
for treatment using statins or other lipid lowering drugs as well
as aspirin to reduce inflammation.
2) Practice heart
healthy eating:
Research has shown that diet does affect cardiovascular health.
Specifically, a poor diet, rich in fats and simple carbohydrates
can build plaques in the arteries and create blockages, which eventually
will result in a heart attack or affect the brain with a stroke.
Following a heart healthy diet that is low in saturated fat, high
in fiber and vegetables, containing many nutrients (anti-oxidants,
vitamins) can prevent the arteriosclerotic process. More information
will follow on the new food pyramid, healthy eating, optimal weight
and girth. Recent medical research proves that cardiovascular disease
can be reversed through diet.
3) Maintain physical fitness:
Research has shown that regular, moderate exercise can positively
influence your LDL, HDL, your mood, your weight, and diabetes. We
recommend a variety of exercise options with tables to determine
the most effective exercise program for you. See lesson four to
learn more the about the risks of inactivity, high blood pressure
and what you can do.
4) Maintain emotional
fitness:
Studies indicate a correlation between depression, hostility,
stress and heart disease. Stress produces hormones that can contribute
to plaque build up in the arteries. We offer you techniques to manage
your stress as well as the latest cognitive approaches for dealing
with hostility and depression. See Session Five to learn new techniques
to deal with stress effectively.
5) Foster friendship
and connection:
Dr. Dean Ornish did the pioneer research that showed the
correlation between a healthy heart and a loving heart. He found
people who were connected with family or friends had less heart
disease than those who are socially isolated. A commitment to foster
social connection through work, volunteerism, spirituality, and
family can boost the immune system and reduce the stresses of living
in today’s complicated world.
Following these 5 Principles of
heart healthy living can help prevent or even reverse heart disease.
Many of us may have to enter a state of TLC – total life style
change.
Note:
Many people put off getting the care that could save lives because
they often do not take the warning signs seriously. Although chest pain is usually
the most common sign, some people have heart attacks without having
chest pain. That is why is important to be aware of other warning
signs as well, such as unexplained dizziness, epigastric
discomfort, left shoulder or jaw pain, shortness of breath without
apparent reason. Anyone who has any of these signs for five
minutes or longer should have medical attention right away. Call an
ambulance (dial 9-1-1) or have someone drive you to the nearest
emergency room, you
could be having a heart attack. Do not drive yourself, it could
be dangerous to you or others.
Many people think a heart attack is sudden
and intense, like in the "movies", where a person clutches his or
her chest and falls over. The truth is that many heart attacks start
slowly, as a mild pain or discomfort. If you feel such a symptom,
you may not be sure what's wrong. Your symptoms may even come and
go. Even those who have had a heart attack may not recognize the
symptoms of the next attack.
Women may think they're not at risk of having a heart attack, but
they are and commonly they have atypical symptoms.
Learn the signs – but also remember
if you're not sure it's a heart attack, you should still have it
checked out. Fast action can save lives – maybe your own.
Act
in time to heart attack signs:
The dramatic, moving stories of three heart
attack survivors and their families illustrate the importance of
heeding heart attack warning signs and seeking medical care quickly.
They vividly convey how a real heart attack may differ from the
stereotypical "movie heart attack" and how getting immediate
treatment can save lives. The warm and sympathetic narration by
an emergency department physician explains what a heart attack is,
the treatments that can save lives if given quickly, why many heart
attack victims delay seeking care, and how to make a heart attack
survival plan. Useful for health fairs, medical waiting rooms, community
groups, and home viewing. Video Play Time: 13 minutes.
Act
in Time To Heart Attack Signs – Video
You must also have RealPlayer version 5.0
or higher on your computer and configured to work with the WWW browser
(Netscape, Internet Explorer, etc). If you do not have RealPlayer,
you may download
a free copy from Real Networks. The latest version is
RealPlayer 8. [Information
about RealPlayer]
Common
questions:
Q: Are there geographical differences
with mortality due to cardiovascular disease among the states in
the USA?
A: Yes.
View
chart.
States colored in red: Mississippi,
Kentucky, Tennessee, West Virginia, Oklahoma, Louisiana, Alabama and
Indiana, have the worst statistics (possibly due to diet ? -rich in
animal fats, too much fried food ?)
Q: How does age affect risk factors?
A: Aging itself should not be considered a risk
factor; however, the older a person gets the longer he/she is exposed
to the risk factors for the development of cardiovascular disease.
Q: Does occupation and level of
education effect risk levels?
A: Yes. Certain occupations that involve high stress
on a continual basis make people more prone to allow the risk factors
to occur. People in jobs that are sedentary often are at greater
risk. Lack of education can put people at higher risk as well.This web site brings
you important information on heart disease to help you strive for
wellness.
Q: Do married people stay healthier?
A: Yes, because they are less isolated, more connected,
and sometimes less stressed due to the emotional support factor.
It can also be said “two heads are better than one”;
therefore, a couple may have more health information at hand.
Q: Do socioeconomic factors influence
cardiovascular heart disease?
A: Absolutely. People with adequate financial means
get help more easily, have access to more information, and have
more time or freedom to attend to health issues. In certain professions
there is little opportunity for education and information. Information
is vital to help people prevent illness. This web site brings you
the latest research and information so that you can be a member
of your own wellness team.
Q: In what countries do people have
less cardiovascular disease than the USA?
View
rankings.
A: Japan has the least heart
disease because they are leaner in general, eat more fish and vegetables
and have a higher degree of activity than in many other countries.
France, Spain and Italy are the next in line in terms of the lowest
incidence of heart disease. It is believed that the social dining
conditions of long and pleasurable meals with lots of conversation
and connection, one or two glasses of red wine, the Mediterranean
diet, as well as a high degree of physical activity helps to keep
these groups more heart healthy.
Q: Are children at risk for cardiovascular
disease?
A: Yes. The lipid profile should be checked in
everyone before the age of 20 especially if there is a family history
of heart disease or high cholesterol.
Q: Are women and men different regarding
cardiovascular disease?
A: Yes. There are substantial differences between
men and women in reference to cardiovascular disease. Some facts
are emerging according to the latest medical research.
For reasons that are unclear, women have
been left out of major research studies in cardiovascular disease
until very recently. Most statistics regarding heart attacks
and strokes have been gathered primarily by studying the male population.
In all fairness this is unjustified since women compose a little
over half of the population.
Time of onset: Cardiovascular
disease usually shows itself 15 years later in women than in
men.
Some of the reasons are:
- There is a protective effect of
female hormones prior to menopause (still debatable).
- Women smoke less than men (at least
until the last few years).
- There are more Type “A”
personalities among men than women.
During the previous century women have been
out of the main work force, therefore they have been somewhat protected
from wear and tear that comes with exposure to stress, hostile environment,
competition, and challenge which cause men to become aggressive
risk takers. However, in modern times women are narrowing the “gap”
very rapidly by entering the man’s world. :Women
in general are gentler, softer, and more patient. They do not discharge
adrenaline as often and as intensively as men do. Women have, as
rule higher levels of HDL- cholesterol. Researchers do not know
why. HDL is known to have a significant protective effect against
arteriosclerosis.
Diagnosis and treatment: Cardiovascular
disease is the leading cause of death among women in this country,
surpassing cancer of the breast and all the other forms of cancer.
However while the incidence of cardiovascular disease mortality
in men has been decreasing since 1970, it is increasing for women.
About 500,000 women per year suffer heart attacks. Of these, 42%
die within a year. Men suffer about 670,000 heart attacks per year,
but only 24% of them die during the first year. The higher mortality
among women after a heart attack has to do with differences in presenting
symptoms, response to treatment, and other factors that relate to
older age at onset of cardiovascular disease.
Symptoms: Symptoms can
be misleading in women. More women than men have chest pain that
is Indistinguishable from angina pectoris, even though they have
normal coronary arteries. (proven by coronary arteriography). Clinicians
underestimate findings and adverse prognostic significance of stress-test
abnormalities found in women. For this reason fewer women are referred
for cardiac catheterization and revascularization procedures after
abnormal stress tests. The presence of risk factors associated with
cardiovascular disease and their control apply equally to men and
women.
Therapeutic procedures
for revascularization (angioplasty, stent placement and coronary
bypass) have a higher rate of complications as well as higher mortality
in women. One reason why women do less well after coronary bypass
may be due to the fact that the internal mammary artery (as opposed
to vein grafts) is less frequently used in them. It is unclear why.
Cardiac rehabilitation
benefits at least 13% of men after a heart attack but only 7% of
women. Physicians refer fewer women for cardiac rehabilitation.
This could also explain why women do less well than men following
a heart attack.
Hormonal Replacement Therapy (HRT):
The latest information regarding risks versus benefits on the use
of HRT in women (typically 0.625-mg estrogens plus 2.5 mg progesterone
daily) is as follows:
Risks:
- More heart attacks and strokes occur
in post-menopausal women during the first year of therapy.
- More breast cancer and more incidents
with blood clots (leg veins and lungs).
Benefits:
- Less cancer of the rectum
and colon.
- Less osteoporosis (therefore less
spine and hip fractures).
- There are some reports that HRT
may delay the onset of Alzheimer disease.
- Less incidence of cancer of the
endometrium.
- Fewer hot flashes.
The proper choice regarding the use of HRT remains a difficult
one to make. Pros and cons have to be carefully weighed. In our
opinion women should make the final decision after all the available
evidence is presented to them. Sometimes hot flashes are so unbearable
that some women are willing to take a chance using hormone replacement
therapy.
There is however a group of medications
used for depression that effectively suppress hot flashes: Paxil,
Celexa, Prozac and Neurontonin, and anti-epileptic drug. Evista,
used for osteoporosis and treatment of Cancer de the breast is also effective
for suppressing hot flashes. More active research in the subject
is being done.
Q: Are we improving?
A: Yes, we are indeed. The average life span in
1900 was only 47 years for men and women. In the year 2000 the life
average has been extended to 74.5 years for men and 79 years for
women. The latest numbers for 2005 show an increase to 77.2 years
for both sexes. This is an increase of 30 years in longevity in
one century! This is due to the great medical advances that have
taken place. Following heart attacks and strokes mortality has declined
do to early diagnosis of the "event ", prompt treatment
with "clot busters", angioplasty, stent implants as well
as other revascularization procedures. These procedures give individuals
a second, third or even higher chance to live. However, the incidence
of arteriosclerosis is not declining because preventive measures
are not being widely used despite our present knowledge.
Updated July 18th,
2007